Cameroon also met then-debutants Guinea-Bissau in their first match two years ago and came from behind to win 2-1 at the start of a campaign that ended in a final triumph over Egypt.
Just ten of the 23-man winning squad are in Egypt, but the figure would have been higher had final matchwinner Vincent Aboubakar not been injured.
In the absence of the Porto forward, Cameroon will look to regular La Liga scorer Karl Toko Ekambi from Villarreal for goals as they pursue back-to-back titles
Africa Cup of Nations 2019 LIVE: Cameroon vs Guinea-Bissau
The full text of our live updates will appear below. They might take a little while to load on slower connections. Please be patient, we apologise for any inconvenience.
Additional reporting by TSA Staff, agencies.